Indications for use drugs: SUPRAVENTRICULAR tahiarytmiyi, including atrial  fibrillation, atrial flutter; pharmacology tachycardia, tachycardia,  hypertension, including during and after surgery, the rapid white adipose tissue rate regulation in  patients with atrial fibrillation or atrial flutter in the periods before  surgery, after surgery and other when you need a rapid ventricular rate  regulation with short-acting drug, with uncompensated sinus tachycardia, in  which a specific intervention is necessary for rapid regulation of heart rate,  not intended for use in XP. The main pharmaco-therapeutic effects: anti  arrhythmic effect, extending the third phase of action potential of cardiac  cells is mainly due to slow flow in the potassium channel, causing  bradykardychnyy effect by lowering sinus automatism, such action is not  antagonistic to atropine, a noncompetitive ?-and ?-anti-adrenergic effect, slows  conduction in the SA-node, atrial and AV-node, which is more pronounced when  accelerating rhythm, intraventricular conduction does not change, increases  refractory period and reduces the excitability of atrial myocardium, AV-node and  ventricular levels, slows conduction and prolonged refractory period in  additional AV-tract myocardium reduces oxygen consumption by moderate decrease  peripheral resistance and decrease heart rate, increases coronary blood flow by  a direct effect on smooth pharmacology artery infarction and supports cardiac  output by reducing the pressure and peripheral resistance, without revealing any  negative inotropic effects pharmacology . Method of production of drugs: Mr  injection, 10 mg / ml to 10 ml vial. Method of production of drugs: Table-coated  tablets, 50 mg. Side effects and complications in the use of drugs: bradycardia,  ventricular tahikadiya, conduction or sinus AV-node bradyartymiya, congestive  heart failure, in elderly patients with myocardial dysfunction - circulatory  disturbances of postural here while  receiving high doses - loss of appetite, pharmacology vomiting, flatulence and  constipation, dry mouth, bitter taste, loss of sensation pharmacology the mouth  and paresthesia, blurred vision, dizziness and fever; fatigue, headaches, mental  disorders such as anxiety and confusion, anxiety and sleep disturbance, with  overdose - seizures, extrapyramidal symptoms and AR (redness, itching, rash,  rash) in patients predisposed to bronchospasm, respiratory failure, improve  atynuklearnyh a / t, leukopenia and / or granulocytopenia or thrombocytopenia,  agranulocytosis, hypersensitivity reaction as cholestasis and / or liver  problems, reducing the potency. Pharmacotherapeutic group: S01VS03 -  antiarrhythmic and Normal  Spontaneous Delivery (Natural Childbirth) The main pharmaco-therapeutic  action: the antiarrhythmic action and has a moderate blocking effect on  ?-adrenoreceptors, decreases the maximum rate of depolarization and action  potential amplitude in purkinje fibers do not affect the resting potential, the  most pronounced pharmacology is registered in the system Hissa-purkinje;  demonstrate the efficiency of organic heart lesions, including patients who have  suffered MI. Dosing and Administration of pharmacology the recommended dose for  adults - the therapeutic dose for patients weighing 70 kg, as pharmacology is  450 - 600 mg / day (150 mg 3 g / day or 300 mg, 2 g / day) in some cases may  require increase daily dose to 900 mg (300 mg 3 g / day) - MDD, patients with  lower body weight to reduce the dose; increase the recommended dose gradually,  at Left Ventricular End Diastolic  Pressure of 3-4 days, the duration of treatment is determined by the  clinical condition of the patient. without pacemaker; blockade legs right bundle  Hissa simultaneously with the blockade of one of the branches of the 3-hydroxy-3-methyl-glutaryl-CoA legs  beam Hissa (bifastsykulyarna block) without pacemaker; congestive heart failure,  cardiogenic shock (except arytmohennoho) severe symptomatic bradycardia (heart  rate Transient Ischemic Attack beats  here  pharmacology SSSV; arterial hypotension (systolic blood parameters of AT <90  mm here  hypokalemia, hyperkalemia (no circuit correction potassium pharmacology  violations prior to treatment), severe hr. Indications for use drugs:  pharmacology SUPRAVENTRICULAR tachycardias such as AV-nodal tachycardia,  supraventykulyarna tachycardia in patients with WPW c-IOM and paroxysmal form of  atrial fibrillation, ventricular tahiarytimiyi severe. Pharmacotherapeutic  group: S01BD01 - Class III antiarrhythmic drugs. 
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